Mississippi Chicken Casserole is a rich, comforting dish inspired by the famous Mississippi-style flavors—savory, tangy, and irresistibly creamy. Featuring tender chicken, buttery goodness, zesty seasonings, and a creamy base, this casserole is perfect for busy weeknights or cozy family dinners.
Mississippi Chicken:
Easy to prepare and full of bold Southern-style flavor, this casserole transforms simple ingredients into a satisfying one-pan meal. It’s hearty, crowd-friendly, and guaranteed to become a regular in your dinner rotation.
History:
The origins of “Mississippi-style” dishes trace back to the wildly popular Mississippi Pot Roast, which became a viral home-cooking sensation in the early 2000s. Known for its use of ranch seasoning, butter, and tangy peppers, the flavor profile quickly inspired variations beyond pot roast. Mississippi Chicken Casserole is a modern adaptation, blending those iconic flavors with chicken and a creamy casserole format. While not a traditional Southern recipe, it reflects contemporary American comfort food with Southern influence.
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Mississippi Chicken Casserole
Ingredients
- 2 cups cooked chicken, shredded or cubed
- 8 oz cream cheese, softened
- 1 cup sour cream
- 1 packet ranch seasoning mix
- ½ cup chicken broth
- ¼ cup unsalted butter, melted
- ½ cup sliced pepperoncini peppers
- 2 tbsp pepperoncini juice
- 1 cup shredded mozzarella or cheddar cheese
- Salt and black pepper, to taste
Instructions
- Preheat oven to 375°F (190°C).
- In a large bowl, mix cream cheese, sour cream, ranch seasoning, chicken broth, and melted butter until smooth.
- Stir in shredded chicken, pepperoncini peppers, and pepperoncini juice.
- Season lightly with salt and black pepper.
- Transfer mixture to a greased baking dish.
- Sprinkle shredded cheese evenly on top.
- Add crushed crackers or breadcrumbs if using.
- Bake for 35–40 minutes until bubbly and lightly golden.
- Rest for 5 minutes before serving.
Notes
- Use rotisserie chicken for convenience.
- Adjust pepperoncini amount for more or less tang.
- Cream cheese should be fully softened for smooth mixing.
- Let casserole rest before serving to set.
- Store leftovers refrigerated in an airtight container.
Tips for Mississippi Chicken:
- Add cooked pasta or rice to make it extra hearty.
- Swap mozzarella for Monterey Jack for more creaminess.
- Broil for 2 minutes at the end for a crispy top.
- Serve with green beans or a fresh salad.
- Make ahead and bake when ready to serve.
FAQs for Mississippi Chicken:
Q1: Is Mississippi Chicken Casserole spicy?
It’s mildly tangy, not spicy. Add extra pepperoncini or chili flakes for heat.
Q2: Can I make this ahead of time?
Yes, assemble it up to 24 hours in advance and refrigerate before baking.
Q3: Can I freeze this casserole?
Yes, freeze before or after baking for up to 2 months.
Q4: What can I serve with this casserole?
Mashed potatoes, rice, or steamed vegetables pair well.
Q5: Can I use raw chicken?
Pre-cooked chicken is recommended for even cooking and best texture.
Conclusion:
Mississippi Chicken Casserole brings together creamy comfort and bold Southern-inspired flavor in one satisfying dish. Easy, hearty, and perfect for sharing, it’s a go-to recipe when you want something warm, filling, and full of personality.